3-chloro-6-bromopyrazine-2-carboxylic acid methyl ester

3-chloro-6-bromopyrazine-2-carboxylic acid methyl ester - Names and Identifiers

Name	Methyl 6-bromo-3-chloro-2-pyrazinecarboxylate
Synonyms	Methyl 6-broMo-3-chloropyrazine-2-carboxylate Methyl 6-bromo-3-chloro-2-pyrazinecarboxylate 6-Bromo-3-chloro-2-pyrazinecarboxylic acid methyl ester 3-chloro-6-bromopyrazine-2-carboxylic acid methyl ester 6-Bromo-3-chloro-pyrazine-2-carboxylic acid methyl ester 2-Pyrazinecarboxylic acid, 6-bromo-3-chloro-, methyl ester
CAS	1256921-67-1
InChI	InChI=1S/C6H4BrClN2O2/c1-12-6(11)4-5(8)9-2-3(7)10-4/h2H,1H3

3-chloro-6-bromopyrazine-2-carboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C6H4BrClN2O2
Molar Mass	251.47
Density	1.772±0.06 g/cm3(Predicted)
Boling Point	289.7±35.0 °C(Predicted)
pKa	-3.78±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-chloro-6-bromopyrazine-2-carboxylic acid methyl ester - Introduction

Methyl 6-bromo-3-chloro-2-pyrazinecarboxylate, chemical formula C10H6BrClN2O2, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
Methyl 6-bromo-3-chloro-2-pyrazinecarboxylate is a colorless to pale yellow solid. It has a high melting and boiling point and is soluble in organic solvents such as alcohols and ethers.

Use:
The compound is commonly used as an intermediate in organic synthesis. It can be used to synthesize other organic compounds, such as drugs, pesticides, etc. In addition, it can also be used as raw materials in industrial fields such as dyes, pigments and coatings.

Method:
there are two main methods for preparing 6-bromo -3-chloro -2-pyrazine methyl formate: one is obtained by the reaction of brominated 3-chloropyridine with methyl formate, and the reaction conditions require higher temperature and longer reaction time; The other is obtained by the reaction of pyrazine formic acid with bromo-methylene chloride, with mild reaction conditions and shorter reaction time.

Safety Information:
6-bromo -3-chloro -2-pyrazine carboxylic acid methyl ester belongs to organic compound, has certain toxicity. When using or contacting this compound, care should be taken to avoid inhaling its vapors or dust, and to avoid direct contact with skin and eyes. When storing and handling the compound, appropriate safety measures, such as wearing protective glasses, masks and gloves, should be taken to ensure that the operating area is well ventilated. In the event of accidental exposure or ingestion of this compound, seek medical attention immediately and bring the compound's label or product instructions.

Last Update：2024-04-09 20:52:54